Positive EFSA Opinion for Mycofix® Ingredient Biomin®BBSH797for All Avian Species
百奧明®BBSH 797獲得歐洲食品安全局（EFSA）在所有家禽中的正面評價
譯者：百奧明中國技術經(jīng)理陳偉光博士
16 January 2017–The European Food Safety Authority (EFSA) has just publisheda positive Scientific Opinion on the safety and efficacy of Biomin® BBSH 797 forthe application in poultry feed.
EFSA acknowledged the efficacy of Biomin®BBSH 797 in safelybiotransformingtrichothecenesinto non-toxic compounds in the gastrointestinaltract of poultry, as demonstrated in numerous feeding trials.
"In vitroand in vivo studies showed that theinclusion of the additive at the recommended dose of 1.7 x 108CFU/kg was effective in reducing contaminating DON in feed whengiven to avian species with a concomitant production of the less toxic de-epoxymetabolite,"read the EFSA Opinion.
EFSA表示，通過體內和體外的研究表明，在家禽飼料中以1.7 x 108 CFU/kg的推薦劑量添加該添加劑，可以有效地降解嘔吐毒素，產(chǎn)生無毒的脫環(huán)氧基化合物。
Beside in vitroand ex vivo studies, the efficacy wasproven by in vivo studies in chickensand turkeys for fattening and laying hens. In all three, the inclusion of theadditive returned the concentration of DON in excreta to or below the levelseen in the uncontaminated control group.
“This is a promising step in achieving an additionalEU authorization for Biomin®BBSH 797.Stringent EFSAguidelines set a high barfor additive manufacturers.BIOMIN is the only company that has providedsufficient in vivo data to prove productefficacy and receive EUauthorization for mycotoxin deactivation,” stated UrsulaHofstetter, Director Competence Center Mycotoxins at BIOMIN.
EFSA just recently published a positive scientific opinionon the safety and efficacy of another Mycofix® ingredient—FUMzyme®— for the application in feedforall avian species in November 2016.
According to recently published scientificfindings (1),more than 79% of 1113 feed and raw commodity samples tested containeddeoxynivalenol.Deoxynivalenol, a member of thetrichothecene family also known as vomitoxin, isa well-known mycotoxin that has been linked to feed refusal, impaired guthealth, diarrhea and pastyvents, decreased resistance to environmental and microbial stressors andincreased susceptibility to disease.
Biomin®BBSH 797 was shown to be safe for birds.According to the opinion, "Chickens for fattening, turkeys for fatteningand laying hens show no adverse effects when the additive is added to diets ateither x10 or x1000 the recommended dose." Furthermore, the "FEEDAPPanel concludes that the additive is safe for the consumer and environment."
Due to the molecular structure of trichothecenes,adsorptive substances, or binders, are not effectiveto counteract trichothecenes.Biomin®BBSH797 isthe first-ever EU authorized microorganism thatbiotransformstrichothecenes into harmless metabolites.
“One thing that makes Mycofix® unique is the biotransformationstrategy, which has been shown to be consistently safe and effective,” said MsHofstetter. Biotransformation works by transforming non-adsorbable mycotoxinsinto harmless substances without any side effects for livestock.
Mycofix® represents the most innovative, broadspectrum product for mycotoxin risk management in livestock. It leverages athree-pronged strategy, including biotransformation, adsorption andbioprotection. Biomin®BBSH 797isthe first-ever EU authorized microorganism thatbiotransformstrichothecenes into harmless metabolites. It received initial EUauthorization for pigs in 2013.
(1) Kovalsky et al.Co-Occurrence of Regulated, Masked and Emerging Mycotoxins and SecondaryMetabolites in Finished Feed and Maize—An Extensive Survey. Toxins 2016, 8,363.
At BIOMIN we harness thepower of science to support animal health and performance. By applyingstate-of-the-art and proprietary technology we deliver natural, sustainable andprofitable solutions to the livestock industry. For over 30 years we havepioneered innovative solutions for mycotoxin risk management and gutperformance. Naturally Ahead.