百奧明®BBSH 797獲得歐洲食品安全局（EFSA）在所有家禽中的正面評(píng)價(jià)

畜牧人市場(chǎng)部1

Positive EFSA Opinion for Mycofix® Ingredient Biomin®BBSH797for All Avian Species

百奧明®BBSH 797獲得歐洲食品安全局（EFSA）在所有家禽中的正面評(píng)價(jià)

譯者：百奧明中國(guó)技術(shù)經(jīng)理陳偉光博士

16 January 2017–The European Food Safety Authority (EFSA) has just publisheda positive Scientific Opinion on the safety and efficacy of Biomin® BBSH 797 forthe application in poultry feed.

2017年1月16日，歐洲食品安全局（EFSA）發(fā)布了Biomin® BBSH 797在家禽飼料中安全性和有效性的正面科學(xué)評(píng)價(jià)。

Genuine biotransformation

EFSA acknowledged the efficacy of Biomin®BBSH 797 in safelybiotransformingtrichothecenesinto non-toxic compounds in the gastrointestinaltract of poultry, as demonstrated in numerous feeding trials.

真正的生物轉(zhuǎn)化

歐洲食品安全局（EFSA）確認(rèn)，Biomin®BBSH 797經(jīng)過大量動(dòng)物實(shí)驗(yàn)驗(yàn)證，能夠在家禽的消化道內(nèi)，安全有效地把單端孢霉烯族類的霉菌毒素生物轉(zhuǎn)化為無毒的代謝產(chǎn)物。

"In vitroand in vivo studies showed that theinclusion of the additive at the recommended dose of 1.7 x 108CFU/kg was effective in reducing contaminating DON in feed whengiven to avian species with a concomitant production of the less toxic de-epoxymetabolite,"read the EFSA Opinion.

EFSA表示，通過體內(nèi)和體外的研究表明，在家禽飼料中以1.7 x 108 CFU/kg的推薦劑量添加該添加劑，可以有效地降解嘔吐毒素，產(chǎn)生無毒的脫環(huán)氧基化合物。

Beside in vitroand ex vivo studies, the efficacy wasproven by in vivo studies in chickensand turkeys for fattening and laying hens. In all three, the inclusion of theadditive returned the concentration of DON in excreta to or below the levelseen in the uncontaminated control group.

此外，該生物降解的有效性，在肉雞、火雞以及蛋雞中已經(jīng)得到驗(yàn)證。在這三種家禽的研究試驗(yàn)中，

該添加劑使家禽排泄物中的嘔吐毒素達(dá)到或者低于沒有嘔吐毒素污染的對(duì)照組。

Absolute protection

“This is a promising step in achieving an additionalEU authorization for Biomin®BBSH 797.Stringent EFSAguidelines set a high barfor additive manufacturers.BIOMIN is the only company that has providedsufficient in vivo data to prove productefficacy and receive EUauthorization for mycotoxin deactivation,” stated UrsulaHofstetter, Director Competence Center Mycotoxins at BIOMIN.

全面保護(hù)

BIOMIN產(chǎn)品總監(jiān)Ursula Hofstetter表示：“Biomin®BBSH 797獲得歐盟的又一項(xiàng)授權(quán)，是前途無量的關(guān)鍵一步。嚴(yán)苛的歐洲食品安全局（EFSA）對(duì)添加劑生產(chǎn)商設(shè)立了高門檻，BIOMIN是唯一一個(gè)給歐盟提供了足夠的體內(nèi)試驗(yàn)數(shù)據(jù)來證明產(chǎn)品功效、并獲得歐盟批準(zhǔn)霉菌毒素解毒劑的公司。”

EFSA just recently published a positive scientific opinionon the safety and efficacy of another Mycofix® ingredient—FUMzyme®— for the application in feedforall avian species in November 2016.

歐洲食品安全局（EFSA）最近剛剛發(fā)布了對(duì)百奧明脫毒劑系列Mycofix®的另一個(gè)成分的科學(xué)正面評(píng)價(jià)—2016年11月FUMzyme®煙曲霉毒素降解酶應(yīng)用在家禽飼料中。

The mycotoxin threat

According to recently published scientificfindings (1),more than 79% of 1113 feed and raw commodity samples tested containeddeoxynivalenol.Deoxynivalenol, a member of thetrichothecene family also known as vomitoxin, isa well-known mycotoxin that has been linked to feed refusal, impaired guthealth, diarrhea and pastyvents, decreased resistance to environmental and microbial stressors andincreased susceptibility to disease.

霉菌毒素的威脅

根據(jù)最近發(fā)表的科學(xué)調(diào)查結(jié)果，在1113份飼料和原料樣品中，嘔吐毒素的陽(yáng)性率超過79%，嘔吐毒素是單端孢霉烯族類霉菌毒素中的一種，眾所周知對(duì)動(dòng)物危害性強(qiáng)，會(huì)導(dǎo)致拒食、腸道損傷、腹瀉、糊肛，降低對(duì)環(huán)境和病原菌的抵抗力，容易感染疾病。

Proven safety

Biomin®BBSH 797 was shown to be safe for birds.According to the opinion, "Chickens for fattening, turkeys for fatteningand laying hens show no adverse effects when the additive is added to diets ateither x10 or x1000 the recommended dose." Furthermore, the "FEEDAPPanel concludes that the additive is safe for the consumer and environment."

被證明的安全性

Biomin®BBSH 797對(duì)家禽是安全的。EFSA的評(píng)價(jià)表示：“根據(jù)建議添加量的10倍或1000倍添加于日糧中，對(duì)于肉雞、火雞和蛋雞，沒有表現(xiàn)出任何不良影響。”此外，歐盟動(dòng)物飼料添加劑和產(chǎn)品評(píng)審組（FEEDAP Panel）認(rèn)為，”該添加劑對(duì)消費(fèi)者和環(huán)境是安全的?！?/div>

Method of choice

Due to the molecular structure of trichothecenes,adsorptive substances, or binders, are not effectiveto counteract trichothecenes.Biomin®BBSH797 isthe first-ever EU authorized microorganism thatbiotransformstrichothecenes into harmless metabolites.

首選的脫毒方式

由于單端孢霉烯族霉菌毒素分子結(jié)構(gòu)的特殊性，吸附劑不能有效地吸附該類毒素。Biomin®BBSH 797是第一個(gè)獲得歐盟批準(zhǔn)的能將單端孢霉烯族霉菌毒素生物降解為無毒代謝產(chǎn)物的微生物。

“One thing that makes Mycofix® unique is the biotransformationstrategy, which has been shown to be consistently safe and effective,” said MsHofstetter. Biotransformation works by transforming non-adsorbable mycotoxinsinto harmless substances without any side effects for livestock.

Ursula Hofstetter女士表示：“百奧明脫毒劑Mycofix®®的獨(dú)特性，是它的生物轉(zhuǎn)化策略，而且被證明是安全和有效的?！鄙镛D(zhuǎn)化針對(duì)不能被吸附的霉菌毒素，轉(zhuǎn)化成無毒成分，對(duì)畜禽沒有任何副作用。

About Mycofix®

Mycofix® represents the most innovative, broadspectrum product for mycotoxin risk management in livestock. It leverages athree-pronged strategy, including biotransformation, adsorption andbioprotection. Biomin®BBSH 797isthe first-ever EU authorized microorganism thatbiotransformstrichothecenes into harmless metabolites. It received initial EUauthorization for pigs in 2013.

關(guān)于Mycofix®

百奧明脫毒劑Mycofix®代表在畜禽霉菌毒素風(fēng)險(xiǎn)管理方面最創(chuàng)新的、廣譜的產(chǎn)品。它綜合了三種策略處理霉菌毒素：生物轉(zhuǎn)化、吸附和生物保護(hù)。Biomin®BBSH 797是首次獲得歐盟授權(quán)的將單端孢霉烯族霉菌毒素生物降解為無毒代謝產(chǎn)物的微生物。在2013年就獲得在豬用產(chǎn)品方面的歐盟授權(quán)。

(1)       Kovalsky et al.Co-Occurrence of Regulated, Masked and Emerging Mycotoxins and SecondaryMetabolites in Finished Feed and Maize—An Extensive Survey. Toxins 2016, 8,363.

Kovalsky等，在飼料和玉米中存在的、隱蔽的和新興的霉菌毒素及次級(jí)代謝產(chǎn)物—霉菌毒素普查報(bào)告，2016,8,363

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This news item isrelevant to poultry.

For additional information on the news that is thesubject of this release, contact media@biomin.netor visit www.biomin.net.

About BIOMIN

At BIOMIN we harness thepower of science to support animal health and performance. By applyingstate-of-the-art and proprietary technology we deliver natural, sustainable andprofitable solutions to the livestock industry. For over 30 years we havepioneered innovative solutions for mycotoxin risk management and gutperformance. Naturally Ahead.